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Table 1 Characteristics of patients at the time of fractionated stereotactic radiotherapy (n = 73)

From: Fractionated stereotactic radiotherapy of brain metastases: results of a retrospective study

Characteristics

Value

Patient age, years, median (Interquartile range, IQR)

61.0 (51.0, 67.5)

Sex, n (%)

 

 Men

40 (54.8%)

 Women

33 (45.2%)

Primary cancer, n (%)

 

 Malignant melanoma

25 (34.2%)

 NSCLC adenocarcinoma

19 (26.0%)

 NSCLC non-adenocarcinoma

7 (9.6%)

 Breast cancer

6 (8.2%)

 Gastrointestinal carcinoma

5 (6.8%)

 Renal cell carcinoma

1 (1.4%)

 Other

10 (13.7%)

Initial UICC stage, n (%)

 

 I

8 (10.9%)

 II

8 (10.9%)

 III

15 (20.5%)

 IV

38 (52.0%)

 Unknown/Missing

4 (5.5%)

Karnofsky performance score, median (IQR)

70 (65, 90)

Systemic treatment * 3 months before/after fractionated stereotactic radiotherapy, n (%)

66 (90.4%)

Number of brain metastases treated with 6x5Gy, median (IQR)

1.0 (1.0, 2.0)

Recursive partitioning analysis (RPA), median (IQR)

2.0 (2.0, 2.5)

Recursive partitioning analysis (RPA), RPA class, n (%)

 

 1

13 (17.8%)

 2

42 (57.5%)

 3

18 (24.7%)

Diagnosis-specific graded prognostic assessment (ds-GPA), median (IQR)

1.5 (1.0, 2.5)

Diagnosis-specific graded prognostic assessment (ds-GPA), groups

 

 0–1.0

21 (28.8%)

 1.5–2.0

30 (41.1%)

 2.5–3.0

21 (28.8%)

 3.5–4.0

1 (1.4%)

Disease control of the primary cancer, n (%)

 

 Yes

53 (72.6%)

 No

11 (15.1%)

 Missing/Unknown

9 (12.3%)

Extracranial metastases, n (%)

 

 Yes

48 (65.8%)

 No

25 (34.2%)

  1. * systemic treatment: chemotherapy, immunotherapy, targeted therapy or anti-hormonal therapy
  2. IQR: interquartile range