Characteristic | No. (%) Or Median (range) |
---|---|
Age (years) | 69 (63–76) |
Sex | Â |
Male | 51 (69%) |
Female | 23 (31%) |
Smoking history | Â |
Current or past smoker | 66 (89%) |
Never smoker | 8 (11%) |
Brinkman index | 840 (500–1105) |
LDH (U/L) | 207 (177–235) |
CRP (mg/dL) | 0.35 (0.08–1.43) |
HbA1c (%) | 5.9 (5.6–6.5) |
Glucose (mg/dL) | 105 (95–121) |
KL-6 (U/mL) | 315 (219–586) |
Histology | Â |
Adenocarcinoma | 37 (50%) |
Squamous cell carcinoma | 26 (35%) |
NSCLC, NOS | 11 (15%) |
Clinical stage | Â |
I | 2 (3%) |
II | 5 (7%) |
IIIA | 22 (30%) |
IIIB | 25 (34%) |
IIIC | 13 (18%) |
IVA | 3 (4%) |
Recurrent | 4 (5%) |
Chemotherapy | Â |
Carboplatin/paclitaxel | 32 (43%) |
Cisplatin/vinorelbine | 20 (27%) |
Other | 4 (5%) |
None | 18 (24%) |
Durvalumab (+) | 23 (31%) |
RT dose | Â |
50Â Gy (2.5Â Gy/1 fr) | 1 (1%) |
60Â Gy | 54 (73%) |
66Â Gy | 19 (26%) |
IMRT | 3 (4%) |
V 20 (%) | 22.3 (17.7–30.5) |
V 5 (%) | 37.6 (29.0–47.0) |
MLD (Gy) | 12.6 (10.2–16.4) |
Vs5 (cc) | 2089 (1476–2626) |
Lung volume (cc) | 3371 (2927–4247) |
ILD onset timing (days) | 85 (59–120) |