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Table 3 Univariate and multivariate logistic regression analysis

From: Preoperative chemoradiation-induced hematological toxicity and related vertebral dosimetry evaluations in patients with locally advanced gastric cancer: data from a phase III clinical trial

 

UVA

MVA

OR (95% CI)

P

OR (95% CI)

P

Grade 3+ Leukopenia

    

V5 (%)

V10 (%)

V20 (%)

V30 (%)

V40 (%)

V45 (%)

1.353 (1.179–1.553)

1.287 (1.133–1.462)

1.171 (1.057–1.297)

1.071 (1.002–1.145)

1.041 (0.986–1.098)

1.037 (0.951–1.132)

0.000

0.000

0.003

0.043

0.147

0.411

  

V5 (%)

V10 (%)

V20 (%)

V30 (%)

V40 (%)

V45 (%)

1.353 (1.179–1.553)

1.287 (1.133–1.462)

1.171 (1.057–1.297)

1.071 (1.002–1.145)

1.041 (0.986–1.098)

1.037 (0.951–1.132)

0.000

0.000

0.003

0.043

0.147

0.411

1.353 (1.179–1.553)

0.000

Grade 3 + Thrombocytopenia

    

VBV (cm³)

Dmin (cGy)

Dmax (cGy)

Dmean (cGy)

1.004 (0.985–1.024)

1.004 (0.998–1.010)

0.999 (0.996–1.003)

1.000 (0.998–1.002)

0.673

0.188

0.607

0.787

  

V5 (%)

V10 (%)

V20 (%)

V30 (%)

V40 (%)

V45 (%)

1.192 (1.074–1.324)

1.115 (1.015–1.244)

0.996 (0.919–1.081)

0.986 (0.937–1.037)

0.986 (0.938–1.036)

0.964 (0.875–1.061)

0.001

0.022

0.930

0.583

0.577

0.452

1.192 (1.074–1.324)

0.001

Grade 3 + HTs

    

VBV (cm³)

Dmin (cGy)

Dmax (cGy)

Dmean (cGy)

1.003 (0.985–1.023)

1.003 (0.998–1.009)

0.996 (0.993-1.000)

0.999 (0.997–1.001)

0.719

0.274

0.055

0.276

  

V5 (%)

V10 (%)

V20 (%)

V30 (%)

V40 (%)

V45 (%)

1.077 (0.982–1.182)

1.044 (0.955–1.141)

0.985 (0.912–1.063)

0.967 (0.923–1.014)

0.967 (0.921–1.015)

0.968 (0.884–1.059)

0.117

0.346

0.692

0.164

0.173

0.474

1.086 (0.987–1.195)

0.042

  1. UVA, univariate logistic regression; MVA, multivariate logistic regression; OR, odds ratio; CI, confidence interval; HT, hematological toxicity