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Fig. 4 | Radiation Oncology

Fig. 4

From: Preoperative chemoradiation-induced hematological toxicity and related vertebral dosimetry evaluations in patients with locally advanced gastric cancer: data from a phase III clinical trial

Fig. 4

(A) ROC curves showing optimal thresholds of vertebral body V5 for Grade 3 + leukopenia, Grade 3 + thrombocytopenia, and Grade 3 + total HTs. The optimal cutoff value were V5 < 91.7% (AUC = 0.86, P < 0.0001), V5 < 89.2% (AUC = 0.76, P < 0.0001), V5 < 88.75% (AUC = 0.70, P = 0.0014), respectively; (B) The predictive efficiency of V5 < 88.75% for Grade 3 + leukopenia (AUC = 0.83), Grade 3 + thrombocytopenia (AUC = 0.76), and Grade 3 + total HTs (AUC = 0.71) in the training cohort; (C) The predictive power of V5 < 88.75% for Grade 3 + leukopenia (AUC = 0.76), Grade 3 + thrombocytopenia (AUC = 0.83), and Grade 3 + total HTs (AUC = 0.74) in the external validation cohort

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Radiation Oncology

ISSN: 1748-717X

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