Table 1 Characteristics of 130 ESCC patients with local primary-recurrence at initial treatment
Variable | Total (%) (n = 130) | Re-RT (n = 30) | Chemotherapy (n = 29) | Esophageal stent (n = 8) | Other treatment (n = 5) | Without treatment (n = 58) |
|---|---|---|---|---|---|---|
Gender | ||||||
Male | 96(73.8) | 24(18.5) | 22(16.9) | 5(3.8) | 5(3.8) | 40(30.8) |
Female | 34(26.2) | 6(4.6) | 7(5.4) | 3(2.3) | 0(0.0) | 18(13.8) |
Age | ||||||
≤ 65 | 57(43.8) | 13(10.0) | 14(10.8) | 3(2.3) | 4(3.1) | 23(17.7) |
> 65 | 73(56.2) | 17(13.1) | 15(11.5) | 5(3.8) | 1(0.8) | 35(26.9) |
PS | ||||||
0/1 | 82(63.1) | 24(18.5) | 18(13.8) | 5(3.8) | 3(2.3) | 32(24.6) |
2 | 48(36.9) | 6(4.6) | 11(8.5) | 3(2.3) | 2(1.5) | 26(20.0) |
T stage | ||||||
1/2 | 19(14.6) | 7(5.4) | 1(0.8) | 0(0.0) | 0(0.0) | 11(8.5) |
3/4 | 111(85.4) | 23(17.7) | 28(21.5) | 8(6.2) | 5(3.8) | 47(36.2) |
N stage | ||||||
0/1 | 107(82.3) | 28(21.5) | 23(17.7) | 7(5.4) | 4(3.1) | 45(34.6) |
2/3 | 23(17.7) | 2(1.5) | 6(4.6) | 1(0.8) | 1(0.8) | 13(10.0) |
Clinical stage | ||||||
I/II | 34(26.2) | 9(6.9) | 7(5.4) | 3(2.3) | 0(0.0) | 15(11.5) |
III/IV | 96(73.8) | 21(16.2) | 22(16.9) | 5(3.8) | 5(3.8) | 43(33.1) |
Tumor location | ||||||
Upper and middle thoracic | 80(61.5) | 17(13.1) | 19(14.6) | 5(3.8) | 4(3.1) | 35(26.9) |
Lower thoracic | 50(38.5) | 13(10.0) | 11(8.5) | 3(2.3) | 1(0.8) | 23(17.7) |
Tumor length(cm) | ||||||
≤ 5 | 66(50.8) | 18(13.8) | 12(9.2) | 5(3.8) | 2(1.5) | 29(22.3) |
> 5 | 64(49.2) | 12(9.2) | 17(13.1) | 3(2.3) | 3(2.3) | 29(22.3) |
Radiotherapy technique | ||||||
IMRT | 51(39.2) | 21(16.2) | 7(5.4) | 3(2.3) | 0(0.0) | 20(15.4) |
VMAT | 79(60.8) | 9(6.9) | 22(16.9) | 5(3.8) | 5(3.8) | 38(29.2) |
Initial radiation dose (Gy) | ||||||
≤ 60 | 75(57.7) | 13(10.0) | 20(15.4) | 4(3.1) | 3(2.3) | 35(26.9) |
> 60 | 55(42.3) | 17(13.1) | 9(6.9) | 4(3.1) | 2(1.5) | 23(17.7) |
Concurrent chemotherapy | ||||||
Yes | 92(70.8) | 22(16.9) | 22(16.9) | 4(3.1) | 5(3.8) | 39(30.0) |
No | 38(29.2) | 8(6.2) | 7(5.4) | 4(3.1) | 0(0.0) | 19(14.6) |
RFI (months) | ||||||
≤ 12 | 80(61.5) | 9(6.9) | 19(14.6) | 6(4.6) | 2(1.5) | 44(33.8) |
> 12 | 50(38.5) | 21(16.2) | 10(7.7) | 2(1.5) | 3(2.3) | 14(10.8) |