Table 2 Summary of immediate side effects

Grade 2

 Nausea

3 (0.7%)

 Cognitive disturbance

1 (0.2%)

 Ataxia

1 (0.2%)

 Dysesthesia

1 (0.2%)

 Dysphasia

1 (0.2%)

 Muscle weakness

4 (0.9%)

 Nervous system disorders—Other (visual field defect)

1 (0.2%)

Grade 3

 Headache

1 (0.2%)

 Nausea

2 (0.5%)

 Seizure (partial)

2 (0.5%)

 Seizure (complex partial or generalized)

2 (0.5%)

 Hydrocephalus

1 (0.2%)

Grade 5

 Intracranial hemorrhage

1 (0.2%)