Pulmonary magnetic resonance-guided online adaptive radiotherapy of locally advanced non-small-cell lung cancer: the PUMA trial

Table 2 Dose Constraints.

Organ at risk	Dose constraints (30–35 fractions)
Brachial plexus	D_max ≤ 60 Gy
Esophagus	D_mean ≤ 34 Gy D_max ≤ 105% of the prescribed dose
Heart	D_mean ≤ 20 Gy V_50Gy ≤ 25%
Non-GTV lung	V_20Gy < 35–40% D_mean ≤ 20 Gy
Spinal cord	D_max ≤ 45 Gy

D_max: maximum dose (appropriate near-maximum dose constraints may be used instead), D_mean: mean dose, V_20/50Gy: Relative organ volume receiving > 20/50 Gy

ISSN: 1748-717X