Table 3 Two formulas concerning the Rad-score
| Â | Radiomics features | Â | Coefficients |
|---|---|---|---|
a. Formulas for calculating pre-treatment Rad-score (RS1) | |||
RS1 =  | original_shape_Elongation | * | − 0.74165845 |
 +  | original_shape_Flatness | * | − 0.19308606 |
 +  | original_glszm_LargeAreaHighGrayLevelEmphasis | * | − 0.96268135 |
 +  | log.sigma.3.mm.3D_firstorder_Skewness | * | − 1.52187110 |
 +  | log.sigma.3.mm.3D_glcm_InverseVariance | * | − 1.05523619 |
 +  | wavelet-HHH_glcm_MCC | * | − 0.65258808 |
 +  | wavelet-HHH_gldm_SmallDependenceLowGrayLevelEmphasis | * | 0.03921352 |
 +  | wavelet-HHH_gldm_DependenceVariance | * | − 0.58868526 |
 +  | wavelet-HHH_glszm_SmallAreaLowGrayLevelEmphasis | * | 0.75365003 |
 +  | wavelet-HLH_firstorder_Mean | * | 0.53801631 |
 +  | wavelet-HLL_glcm_Autocorrelation | * | 2.09368963 |
 +  | wavelet-LHH_firstorder_Skewness | * | 1.09442341 |
 +  | wavelet-LHH_glcm_Imc1 | * | − 0.58413612 |
 +  | wavelet-LLH_glcm_Idmn | * | − 0.32246341 |
b. Formulas for calculating post-treatment Rad-score (RS2) | |||
RS2 =  | log.sigma.2.mm.3D_ngtdm_Contrast | * | 0.33057259 |
 +  | log.sigma.3.mm.3D_glszm_SizeZoneNonUniformity | * | 0.68298741 |
 +  | wavelet-HHH_firstorder_Median | * | − 2.91041062 |
 +  | wavelet-HLH_gldm_LargeDependenceHighGrayLevelEmphasis | * | 0.07259247 |
 +  | wavelet-LLH_glcm_Autocorrelation | * | 0.06522993 |
 +  | wavelet-LLL_glcm_ClusterProminence | * | 0.25489697 |
 +  | wavelet-LLL_glcm_DifferenceVariance | * | 1.49013870 |