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Fig. 3 | Radiation Oncology

Fig. 3

From: Systematic in vitro analysis of therapy resistance in glioblastoma cell lines by integration of clonogenic survival data with multi-level molecular data

Fig. 3

Integration of global mRNA expression data with scores of inherent therapy resistance in human glioblastoma cell lines. a Graphical representation of genes whose log2 mRNA expression levels show strong positive or negative correlation (|R|≥ 0.9) with inherent resistance to single-shot RTX, fractionated RTX, TMZ, and single-shot RTX + TMZ in human glioblastoma cell lines. Only genes with an average log2 expression value of 6 or higher compared to astrocytes are shown. b Intersect analysis of genes whose log2 mRNA expression shows significant positive or negative correlation (|R|≥ 0.9) with inherent resistance to single-shot RTX (blue), fractionated RTX (red), TMZ (green), and single-shot RTX + TMZ (yellow)

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Radiation Oncology

ISSN: 1748-717X

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