Evaluation of quality of life in lung cancer patients receiving radiation and Viscum album L.: a real-world data study

Table 3 EORTC QLQ-C30 questionnaires of the entire study cohort at first diagnosis (T0) and 12 months thereafter (T1)

EORTC QLQ-C30	Key	T0		T1		T0–> T1
n = 112	Key	Mean	SD	Mean	SD	Changes	IQR	p-values
Global health status/QoL	QL	47.92	21.40	54.28	24.43	6.46	− 8.3 to 16.7	0.006*
Physical functioning	PF	62.70	24.79	58.15	24.95	− 4.56	− 20.0 to 13.3	0.063
Role functioning	RF	54.35	34.57	52.23	34.47	− 2.25	− 16.7 to 16.7	0.531
Emotional functioning	EF	50.61	22.55	58.04	28.30	7.58	− 8.3 to 25.0	0.006*
Cognitive functioning	CF	59.70	27.00	57.59	28.25	− 1.82	− 16.7 to 16.7	0.495
Social functioning	SF	60.49	30.81	57.89	32.27	− 3.40	− 16.7 to 16.7	0.269
Fatigue	FA	52.83	27.39	53.87	26.15	0.91	− 11.1 to 11.1	0.737
Nausea and vomiting	NV	10.06	19.41	10.42	20.79	0.45	0–0	0.845
Pain	PA	37.74	35.56	38.39	33.98	0.63	− 16.7 to 33.3	0.860
Dyspnea	DY	52.73	37.97	54.65	36.57	1.53	− 33.3 to 33.3	0.680
Insomnia	SL	47.04	36.73	42.26	37.79	− 5.61	− 33.3 to 33.3	0.171
Appetite loss	AP	38.84	35.12	30.36	37.68	− 9.17	− 33.3 to 0	0.015*
Constipation	CO	26.67	37.01	21.32	32.51	− 5.20	− 33.3 to 0	0.159
Diarrhea	DI	13.03	26.63	15.32	25.23	2.45	0–0	0.426
Financial difficulties	FI	20.32	29.28	27.38	30.61	6.98	0–33.3	0.01*

EORTC QLQ-C30 European Organisation for Research and Treatment of Cancer quality-of-life questionnaire; IQR Interquartile range; n number of patients; SD standard deviation. p-values (two-sided, paired t-test) for longitudinal changes between T0 and T1
Significant p-values are indicated: *p-value < 0.05

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