Non-classic radiation-induced liver disease after intensity-modulated radiotherapy for Child–Pugh grade B patients with locally advanced hepatocellular carcinoma

Table 3 Post-RT hepatotoxicity metrics

Variable	n	%
Liver function metrics
CP Score + 1 or more	28	37.3
CP Score + 2 or more	15	20.0
CP Class Change	8	10.4
ALBI Grade + 1 or more	11	14.6
CTCAE 5.0 laboratory toxicities
T-Bili ≥ G2	10	13.3
T-Bili G3	4	5.3
AST ≥ G2	7	9.3
AST G3	3	4.0
ALT ≥ G2	5	6.7
ALT G3	2	2.7
ALP ≥ G2	3	4.0
ALP G3	0	0
PLT ≥ G2	17	22.7
PLT G3	7	9.3
ncRILD	17	22.7

Data are n (%)
ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CP, Child–Pugh; CTCAE 5.0, the Common Terminology Criteria for Adverse Events of the National Cancer Institute v5.0; PLT, platelets; G1, grade1; G2, grade2; G3, grade3; ncRILD, non-classic radiation-induced liver disease; RT, radiotherapy; T-Bili, total bilirubin

ISSN: 1748-717X