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Table 2 Baseline clinical and dosimetric characteristics (continuous variables)

From: Clinical outcomes and lung toxicities after lung SABR using dynamic conformal arc therapy: a single-institution cohort study

Variables

Mean

Median

Range

SD

Age (y.o)

71.2

72.0

46–90

9.8

Smoking pack years

45.9

40.0

5–130

23.7

Tumor size (mm)

18.3

15.0

6.0–74

10.7

FEV1a (%)

72.9

72.0

20–125

24.2

KCOb (%)

71.0

68.5

15.0–118

23.3

ITV (cc)

9.5

4.6

0.5–115.3

14.8

PTV (cc)

25.7

17.8

2.20–167

24.4

PTV coverage (%)

95.1

96.4

71.5–99.7

4.7

PDmed

0.23

0.22

0.09–0.49

0.1

Conformity Index

0.81

0.79

0.54–0.93

0.1

Gradient index

5.9

5.57

3.43–11.18

1.72

ITV D2% (Gy)

62.6

62.3

41.2–73.7

3.8

BED10 ITV D2% (Gy)

153.5

139.6

62.4–232.4

36.8

ITV D98% (Gy)

56.2

56.2

38.5–63.5

3.4

BED10 ITV D98% (Gy)

129.9

119.4

57–190.1

29.2

ITV Dmax (Gy)

64.0

63.6

42.2–75.8

3.9

BED10 ITV Dmax (Gy)

159.1

144.5

64.5–240.2

38.4

ITV Dmed (Gy)

60.0

59.9

39.8–69.9

3.5

BED10 ITV Dmed (Gy)

143.4

131.7

59.6–209.6

32.9

ITV Dmean (Gy)

59.8

59.8

39.8–69.7

3.6

BED10 ITV Dmean (Gy)

142.8

131.3

59.6–208.0

33.2

PTV D2% (Gy)

62.0

61.8

41.2–73.2

3.7

BED10 PTV D2% (Gy)

151.4

138.2

62.4–226.0

35.8

PTV D98% (Gy)

49.5

49.4

36.0–58.6

3.2

BED10 PTV D98% (Gy)

106.4

98.2

54.5–155.4

24.3

PTV Dmax (Gy)

64.0

63.6

43.0–75.8

3.8

BED10 PTV Dmax (Gy)

159.1

144.5

66.1–240.2

38.4

PTV Dmean (Gy)

56.2

56.2

39.3–65.7

3.0

BED10 PTV Dmean (Gy)

129.1

120.3

58.6–186.6

28.1

PTV Dmed (Gy)

56.2

56.4

39.4–66.5

3.0

BED10 PTV Dmed (Gy)

129.1

119.4

58.8–187.6

27.6

MLDt (Gy)

3.4

3.1

0.10–19.9

1.9

Vt20 (%)

3.9

3.5

0.80–10.3

2.1

Vt12.5 (%)

7.1

6.7

1.7–18.6

3.4

Vt5 (%)

15.9

14.7

3.5–36.5

6.7

MLDi (Gy)

5.4

5.0

1.6–27.8

2.8

Vi20 (%)

7.7

6.5

1.5–30.0

4.4

Vi12.5 (%)

13.9

13.0

3.3–35.9

6.8

Vi5 (%)

26.0

25.2

7.2–48.1

9.3

  1. FEV1 forced expiratory volume in one second, KCO diffusion capacity of the lung for carbon monoxide, ITV internal target volume, PTV planning target volume, BED10 biologically effective dose with alpha/beta of 10, PDmed median pulmonary density around the PTV, LD mean lung dose, t total (2 lungs), i ipsilateral lung, Dmed median dose, Dmean mean dose, SD standard deviation
  2. aData available in 113 patients
  3. bData available in 82 patients