Table 1 Summary of general study and publication characteristics
From: A focused review of statistical practices for relating radiation dose-volume exposure and toxicity
Characteristic | N(%) of 325 |
|---|---|
Journal | |
 Int J Radiat Oncol Biol Phys | 103 (31.7) |
 Radiother Oncol | 103 (31.7) |
 Pract Radiat Oncol | 36 (11.1) |
 Radiat Oncol | 55 (16.9) |
 Acta Oncol | 28 (8.6) |
Year of Publication | |
 2015 | 46 (14.2) |
 2016 | 49 (15.1) |
 2017 | 59 (18.2) |
 2018 | 43 (13.2) |
 2019 | 55 (16.9) |
 2020 | 31 (9.5) |
 2021 | 42 (12.9) |
Data Source | |
 Clinical trial | 48 (14.8) |
 Prospective cohort | 39 (12.0) |
 Retrospective cohort | 224 (68.9) |
 Case control | 8 (2.4) |
 Other | 6 (1.8) |
Sample Size | |
  < 100 | 124 (38.2) |
 100–499 | 157 (48.3) |
 500–999 | 29 (8.9) |
  ≥ 1,000 | 15 (4.6) |
Radiation Modality | |
 External Beam | 300 (92.3) |
 Brachytherapy | 15 (4.6) |
 Both | 10 (3.1) |
Study Outcome1 | |
 Pulmonary morbidity | 41 (12.6) |
 Impaired liver function | 10 (3.1) |
 Lower GI morbidity | 46 (14.2) |
 Urinary morbidity | 33 (10.2) |
 Brain necrosis | 17 (5.2) |
 Hematologic morbidity | 24 (7.4) |
 Cardiac morbidity | 22 (6.8) |
 Chest wall pain | 9 (2.8) |
 Esophagitis | 14 (4.3) |
 Xerostomia | 11 (3.4) |
 Swallowing function | 13 (4.0) |
 Non-cancer death | 13 (4.0) |
 Other | 120 (36.9) |