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Table 2 Dosimetric parameters related to hyper-fractionated radiotherapy for the target lesion

From: Dosimetric and clinical analysis of pseudo-progression versus recurrence after hypo-fractionated radiotherapy for brain metastases

Parameters

Median

Mean ± standard deviation

Minimum

Maximum

BED (Gy)

72.8

74.5 ± 15.5

39.0

152.0

TC (%)

95.7

93.9 ± 7.5

55.0

100.0

PITV

1.2

1.5 ± 1.0

0.7

10.2

CI

0.7

0.7 ± 0.2

0.1

1.0

HI

0.1

0.2 ± 0.1

0.0

0.6

GI

3.8

4.5 ± 1.0

0.7

10.2

Dose dropping zone Dmean (Gy)

53.9

51.1 ± 12.9

12.2

94.4

Dose dropping zone V95 (%)

98.0

89.5 ± 16.4

6.1

100.0

Normal brain tissue Dmean BED (Gy) in HFRT group

3.7

4.8 ± 3.9

0.2

17.4

Normal brain tissue Dmean BED (Gy) in WBRT + HFRT group

49.4

35.8 ± 21.8

2.5

59.8

  1. BED Biological equivalent dose, TC Target coverage, PITV Prescription isodose target volume ratio, CI Conformity index, HI Homogeneity index, GI Gradient index, Dmean The mean dose, V95 the volume that received 95% of the prescribed dose, V30 the volume receiving 30 Gy irradiation