Table 3 Side effect by proton therapy
| Â | Â | 50Â Gy group | 40.05Â Gy group | p-value |
|---|---|---|---|---|
Leukopenia | Â | Â | Â | 0.441 |
|  | Grade 1 | 2 | 9 | – |
|  | Grade 2 | 4 | 3 | – |
|  | Grade 3 | 2 | 0 | – |
Neutropenia | Â | Â | Â | 0.03 |
|  | Grade 1 | 2 | 2 | – |
|  | Grade 2 | 3 | 3 | – |
|  | Grade 3 | 2 | 0 | – |
Anemia | Â | Â | Â | 0.201 |
|  | Grade 1 | 0 | 4 | – |
|  | Grade 2 | 0 | 0 | – |
|  | Grade 3 | 0 | 0 | – |
Radiodermatitis | Â | Â | Â | 0.000 |
|  | Grade 1 | 5 | 33 | – |
|  | Grade 2 | 8 | 3 | – |
|  | Grade 3 | 1 | 0 | – |
Radioaction-induced esophagitis | Grade 1 | 6(85.7%) | 3(60%) | 0.356 |
Itching or tingling of the skin |  | 6 | 7 | – |
Swelling in the arm |  | 1 | 2 | – |
Swelling in the mammary gland |  | 4 | 2 | – |
Mammary gland to harden |  | 8 | 19 | – |
Breast pain |  | 2 | 4 | – |
Radiation pneumonitis | Â | Â | Â | 0.230 |
|  | Grade 1 | 0 | 3 | – |
|  | Grade 2 | 0 | 1 | – |
Hypothyroidism | Â | 0 | 1 | 0.538 |
Rib fracture | Â | 0 | 2 | 0.378 |