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Table 1 Patient characteristics (n = 184)

From: Acute toxicities and cumulative dose to the brain of repeated sessions of stereotactic radiotherapy (SRT) for brain metastases: a retrospective study of 184 patients

Characteristic

Sex

Male

91

49.5%

Female

93

50.5%

Control of the primary tumor site

Yes

109

59.2%

No

75

40.8%

Primary cancer

Lung

103

56%

Adenocarcinoma

69

67%

Epidermoid

19

18.4%

Small cell

4

3.9%

Undifferentiated

4

3.9%

Other

7

6.8%

Breast

24

13%

Luminal A

5

20.8%

Luminal B

5

20.8%

Her2 + 

11

45.8%

Triple negative

3

12.5%

Melanoma

24

13%

Kidney

8

4.35%

Digestive

16

8.7%

Other

9

4.95%

Patient characteristics at SRT1

Median age (range)

61

24–88

Median WHO grade (range)

1

0–3

Median KPS score in % (range)

90

40–100

Median DS-GPA (range)

2.5

0–4

Median RPA (range)

2

1–3

Extracerebral progression

117

64%

Systemic treatment

129

70%

Median number of BMs (range)

1.5

1–10

Median volume of BMs (in mL) (range)

0.8

0.1–48.6

Tumor bed radiosurgery

70

38%

Patient’s worst/all characteristics

Worst DS-GPA

2

0–4

Worst RPA

2

1–3

Immunotherapy all time

25

14%

Targeted therapy all time

43

23%

BMV grade

  

Low

103

56%

Intermediate

69

37.5%

High

12

6.5%

Salvage WBRT

34

18%

Local recurrence

57

31%

Radionecrosis

42

23%

  1. Italic values represent a subgroup of the set cited in the row above