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Table 1 Patient characteristics (n = 176)

From: Feasibility of linac-based fractionated stereotactic radiotherapy and stereotactic radiosurgery for patients with up to ten brain metastases

 

All cases (n = 176)

Group A: one tumor (n = 78)

Group B: two to four tumors (n = 67)

Group C: five to ten tumors (n = 31)

p value

Age (years)

    

0.156

Median

69.5

69.6

71.3

68.5

 

(range)

(19–90)

(23–88)

(19–90)

(21–82)

 

 < 65

49 (27.8%)

25 (32.1%)

13 (19.4%)

11 (35.5%)

 

 ≥ 65

127 (72.2%)

53 (67.9%)

54 (80.6%)

20 (64.5%)

 

Gender

    

0.73

Male

97(55%)

43(55%)

35(52%)

19(61%)

 

Female

79(45%)

35(45%)

32(48%)

12(39%)

 

Primary sites

    

0.952

Lung

111(63%)

48(61.5%)

45(67%)

18(58%)

 

GI

20(11%)

9(11.5%)

6(9%)

5(16%)

 

Breast

8(5%)

4(5%)

3(4%)

1(3%)

 

Others

37(21%)

17(22%)

13(20%)

7(23%)

 

KPS

    

0.604

 ≥ 80

96(55%)

46(59%)

34(51%)

16(52%)

 

 ≤ 70

80(45%)

32(41%)

33(49%)

15(48%)

 

RPA

    

0.24

1

11(6%)

6(8%)

2(3%)

3(10%)

 

2

119(68%)

56(72%)

46(69%)

17(55%)

 

3

46(26%)

16(20%)

19(28%)

11(35%)

 

Extracranial

    

0.124

Lesions

Controlled

50(28%)

27(35%)

18(27%)

5(16%)

 

Uncontrolled

126(72%)

51(65%)

49(73%)

26(84%)

 

fSRT or SRS

    

0.846

SRS

97(55%)

44(56%)

35(52%)

18(58%)

 

fSRT

79(45%)

34(44%)

32(48%)

13(42%)

 

Systemic

    

0.55

Therapy

Yes

44(56%)

42(63%)

16(52%)

102(58%)

 

No

34(44%)

25(37%)

15(48%)

74(42%)

 

Total PTV

    

0.022

volume (cm3)

1 (≥ 15)

42(24%)

11(14%)

19(28%)

12(39%)

 

2 (≥ 4, < 15)

68(39%)

33(42%)

22(33%)

13(42%)

 

3 (< 4)

66(37%)

34(44%)

26(39%)

6(19%)

 
  1. GI Gastrointestinal cancers, KPS Karnofsky performance status, RPA Recursive partitioning analysis, fSRT Fractionated stereotactic radiotherapy, SRS Stereotactic radiosurgery PTV Planning target volume