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Table 2 Clinical outcomes of patients with OAL treated with ultra-low-dose RT

From: Ultra-low-dose radiotherapy in the treatment of ocular adnexal lymphoma: a prospective study

Comm treatment

Patients (n = 16), n (%)

Follow-up Time (mo)

 Median (range)

15.5 (5.0–30.0)

Best corrective visual acuity

 Baseline, Median (range)

20/35 (20/20-LP)

 Final, Median (range)

20/30 (20/20-HM)

Lesion Area (mm2)

 

Baseline

203.8 ± 92.2

Post-operation

117.9 ± 60.4*

Initial evaluation post-RT

38.7 ± 46.0#

One year post RT (n = 13)

 

With regression (n = 11)

8.5 ± 21.2#

With recurrence (n = 2)

191.7 ± 13.9

Local response at initial evaluation (n = 16)

 

Complete regression

9 (56)

Partial regression

7 (44)

 Progression

0 (0)

Local response at 6 months (n = 14)

 

Complete regression

11 (79)

Partial regression

2 (14)

Progression

1 (7)

Time to Complete regression (mo)

 Median (range)

2.0 (1.0–7.3)

Time to recurrence (mo)

 Median (range)

7.5 (3.0–12.0)

Disease status at last follow-up

 Complete regression

13 (81)

 Alive with disease

3 (19)

 Dead due to lymphoma

0 (0)

 Dead due to causes other than lymphoma

0 (0)

Progression-free survival at one year (%)

85

Progression-free survival (mo)

 Median (range)

15.5 (5.0–24.0)

Ocular toxicity (n = 16)

 

 Acute toxic effect

0 (0)

 Chronic toxic effect

0 (0)

  1. OAL ocular adnexal lymphoma, RT radiation therapy
  2. *P < 0.01 compared with baseline lesion area; #P < 0.01 compared with postoperative lesion area