Parameter | OAR doses | Dose differences rate (p value) | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
IMRT | IMRT-BMS | IMPT | IMPT-BMS | IMRT versus IMPT | IMRT versus IMRT-BMS | IMPT versus IMPT-BMS | IMRT-BMS versus IMPT-BMS | IMRT-BMS versus IMPT | IMRT versus IMPT-BMS | |
Bladder | ||||||||||
V40 | ||||||||||
Median | 25.1 | 27.8 | 24.3 | 21.5 | − 3.2% | 10.8% | − 11.5% | − 22.7% | − 12.6% | − 14.3% |
(min–max) | (10.4–37.5) | (14.5–40.2) | (10.9–36) | (10.3–36.6) | < 0.001 | 0.24 | 0.001 | < 0.001 | < 0.001 | < 0.001 |
Dmean | ||||||||||
Median | 34.6 | 34.4 | 28.7 | 28.9 | − 17.1% | − 0.6% | 0.7% | − 16.0% | − 16.6% | − 16.5% |
(min–max) | (28.7–37.7) | (28.8–38.2) | (20.8–34.5) | (20.5–34.6) | < 0.001 | 0.879 | 0.106 | < 0.001 | < 0.001 | < 0.001 |
Femur head—L | ||||||||||
V30 | ||||||||||
Median | 9.3 | 6.2 | 5.2 | 5.1 | − 44.1% | − 33.3% | − 1.9% | − 17.7% | − 16.1% | − 45.2% |
(min–max) | (0–14.6) | (1.3–15.4) | (0.4–17.9) | (0.1–12.9) | 0.503 | 0.126 | 0.016 | 0.003 | 0.469 | 0.001 |
Dmean | ||||||||||
Median | 19.5 | 19.6 | 19 | 18.8 | − 2.6% | 0.5% | − 1.1% | − 4.1% | − 3.1% | − 3.6% |
(min–max) | (15.7–19.8) | (17.6–19.9) | (13.2–19.3) | (13.1–19.4) | < 0.001 | 0.081 | 0.427 | < 0.001 | < 0.001 | < 0.001 |
Femur head—R | ||||||||||
V30 | ||||||||||
Median | 8.8 | 5.7 | 5.2 | 5.1 | − 40.9% | − 35.2% | − 1.9% | − 10.5% | − 8.8% | − 42.0% |
(min–max) | (0–14.6) | (1.3–17) | (0.1–20.1) | (0.1–12.5) | 0.136 | 0.079 | 0.028 | 0.004 | 0.9 | < 0.001 |
Dmean | ||||||||||
Median | 19.6 | 19.5 | 19.1 | 19 | − 2.6% | − 0.5% | − 0.5% | − 2.6% | − 2.1% | − 3.1% |
(min–max) | (17.2–19.8) | (16.1–19.8) | (11–19.3) | (10.9–19.4) | < 0.001 | 0.611 | 0.865 | < 0.001 | < 0.001 | < 0.001 |
Rectum | ||||||||||
V30 | ||||||||||
Median | 71.8 | 82 | 65.6 | 62 | − 8.6% | 14.2% | − 5.5% | − 24.4% | − 20.0% | − 13.6% |
(min–max) | (36.5–96.9) | (37.4–97.8) | (23.3–70.2) | (22.8–70.5) | < 0.001 | 0.299 | 0.001 | < 0.001 | < 0.001 | < 0.001 |
V40 | ||||||||||
Median | 33.8 | 35.5 | 34.4 | 32.8 | 1.8% | 5.0% | − 4.7% | − 7.6% | − 3.1% | − 3.0% |
(min–max) | (6.9–37.1) | (8.1–40.4) | (11.3–37.1) | (9.6–37.8) | 0.823 | 0.248 | 0.211 | < 0.001 | 0.001 | 0.761 |
Dmean | ||||||||||
Median | 35.6 | 36.7 | 34.1 | 33.9 | − 4.2% | 3.1% | − 0.6% | − 7.6% | − 7.1% | − 4.8% |
(min–max) | (28.3–38.4) | (28.6–38.9) | (23–36.1) | (23.1–35.5) | < 0.001 | 0.053 | 0.03 | < 0.001 | < 0.001 | < 0.001 |