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Fig. 1 | Radiation Oncology

Fig. 1

From: Intensity modulated proton therapy for early-stage glottic cancer: high-precision approach to laryngeal function preservation with exceptional treatment tolerability

Fig. 1

63-year-old male patient with T2N0 glottic carcinoma originating in the left vocal cord with restricted vocal cord mobility and field cancerization with severe squamous epithelial dysplasia affecting also the left supraglottis. The patient was treated with intensity modulated proton therapy (IMPT) with a dose of 63 Gy relative biological effectiveness (RBE) in 35 fractions of 1.8 Gy RBE with a simultaneous integrated boost to the tumor region up to a total dose of 70 Gy RBE with contralateral arytenoid and carotid artery sparing. In the first follow-up six weeks after IMPT, a complete remission was shown clinically and by imaging. Laryngoscopy showed laryngeal edema with fibrin coatings in the arytenoid region, the piriform sinus and the vocal cords on both sides. Although the glottic closure was still incomplete during phonation, the mobility of the vocal cords was improved

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Radiation Oncology

ISSN: 1748-717X

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