Skip to main content

Table 3 Comparison between large- and medium-breast cases

From: Dummy run quality assurance study in the Korean Radiation Oncology Group 19 − 09 multi-institutional prospective cohort study of breast cancer

   

WBI

WBI + RNI

   

Large breast

Medium breast

p -value

Large breast

Medium breast

p -value

Target

Breast Lt

D95% (%)

97.4 (91.1-100.2)

96.7 (91.6-105.8)

0.7508

97.9 (91.4-104.8)

97.8 (91.8-106.4)

0.8399

 

CTVn-intpect

D95% (%)

3.7 (1.6–15.0)

1.9 (1.1–5.7)

0.0566

98.2 (10.3-106.3)

96.0 (4.0-104.1)

0.3123

 

CTVn-L1

D95% (%)

6.0 (2.6–78.4)

2.9 (1.2–22.9)

0.0304

73.7 (6.9–99.7)

47.2 (3.2-100.6)

0.3708

 

CTVn-L2

D95% (%)

2.9 (1.3–11.4)

1.6 (0.8-5.0)

0.0605

94.7 (15.6-101.8)

95.4 (6.6-102.6)

0.7508

 

CTVn-L3

D95% (%)

2.8 (1.2–8.3)

1.4 (0.7–4.4)

0.0606

96.8 (83.1-103.6)

94.6 (91.0-102.0)

0.3708

 

CTVn-L4

D95% (%)

1.8 (0.6–5.4)

1.1 (0.4–3.7)

0.4704

93.7 (27.1-102.3)

94.1 (33.9–104.0)

0.7508

 

CTVn_IMN

D95% (%)

4.1 (1.6–17.3)

3.6 (1.4–15.5)

0.9539

10.8 (3.3–43.3)

13.5 (5-50.6)

0.6236

OAR

Lung Lt

V20Gy (%)

17.6 (6.7–31.7)

13.1 (8.1–25)

0.2602

32.4 (16.3–60.1)

27.7 (20.5–57.4)

0.2602

 

Heart

Mean dose (Gy)

5.1 (1.6–10.6)

3.6 (1.3–9.2)

0.1749

6.4 (2.0-15.3)

6.8 (1.7–14.3)

0.7508

 

Breast Rt

D5% (Gy)

0.7 (0.1–4.8)

1.4 (0.3–6.4)

0.1332

1.3 (0.2–7.7)

1.8 (0.4–15.4)

0.1841

 

LAD-coronary a

V20Gy (%)

39.4 (6.1–42.6)

45.1 (38.1–52.7)

0.0024

41.6 (7.8–43.1)

48.2 (40.5–53.7)

0.0007

 

sh joint + 1 cm

V5Gy (%)

0.0 (0.0-19.7)

0.0 (0.0-1.5)

0.8389

38.5 (7.9–94.7)

38.8 (3.3–97.3)

0.977

  1. WBI, whole breast irradiation; WBI + RNI, whole breast irradiation plus regional node irradiation; Breast Lt, Breast left; D95%, minimum dose delivered to 95% of the structure; CTVn-intpect, interpectoral node clinical target volume; CTVn-L1-4, axillae level 1–4 clinical target volume; CTVn-IMN, internal mammary node clinical target volume; OAR, organs at risk; Lung Lt, Lung left; V20Gy, volume receiving 20 Gy; Breast Rt, Breast right; D5%, minimum dose delivered to 5% of the structure; LAD_coronary a, left anterior descending coronary artery; sh joint + 1 cm, shoulder joint with 1 cm margin; V5Gy, volume receiving 5 Gy