Skip to main content
Fig. 2 | Radiation Oncology

Fig. 2

From: ΔNp63α transcriptionally represses p53 target genes involved in the radiation-induced DNA damage response

Fig. 2

RNA transcriptome analysis of HMECs. (a) Left: K-means clustering heatmaps showing gene expression in siRNA-treated HMECs at 24 h post-irradiation. Right: Pathway enrichment analysis of scr- and sip63-treated groups in each cluster based on the Gene Ontology (GO) biological process database. Clusters A and B contain 295 and 205 genes, where upregulated and downregulated genes are depicted in red and blue, respectively. (b) Biclustering analysis based on the BCCC method for siRNA-treated HMECs at 24 h post-irradiation

Back to article page