Table 2 CTV D_max, HI, CI, V95 and anorectum/bladder V_4000cGy, V_6500cGy, and V_8000cGy dose statistics for all cohorts analyzed

CTV D_max

Mean

110.0 ± 1.7

108.0 ± 1.6

109.7 ± 1.8

110.0 ± 1.7

106.8 ± 1.1

110.0 ± 1.8

108.7 ± 1.9

Range

107.4–113.8

104.5–110.6

106.8–113.8

106.7–114.5

104.2–110.0

106.7–114.4

104.0–114.6

Failure rate of uncertainty plans (%)

0.0

 0.0

 0.0

 0.0

CTV homogeneity index (HI)

Mean

0.05 ± 0.01

0.03 ± 0.01

0.05 ± 0.01

0.05 ± 0.01

0.06 ± 0.02

0.07 ± 0.03

0.09 ± 0.04

Range

0.03–0.08

0.02–0.04

0.03–0.06

0.03–0.10

0.01–0.10

0.04–0.25

0.04–0.26

CTV conformity index (CI)

Mean

1.8 ± 0.1

1.5 ± 0.1

1.7 ± 0.2

1.8 ± 0.1

1.2 ± 0.1

1.8 ± 0.1

1.5 ± 0.2

Range

1.6–2.0

1.2–1.7

1.4–2.0

1.6–2.0

0.8–1.6

1.6–2.0

1.0–2.0

CTV V95%

Mean

99.9 ± 0.1

100.0 ± 0.0

100.0 ± 0.0

99.9 ± 0.2

99.6 ± 0.4

99.7 ± 0.7

98.8 ± 1.2

Range

99.7–100.0

100.0

100.0

98.3–100.0

97.5–100.0

94.5–100

95.4–100

Failure rate of uncertainty plans (%)

0.0

 0.0

 0.0

 0.0

Anorectum (V_4000cGy)

Mean

20.4 ± 6.3

13.8 ± 4.4

15.3 ± 5.3

20.7 ± 8.2

14.0 ± 6.2

21.2 ± 10.2

15.8 ± 9.0

Range

10.4–32.7

6.6–22.8

7.7–27.9

5.00–45.7

3.0–32.0

2.1–53.7

1.7–42.5

Failure rate of uncertainty plans (%)

4.6

 0.0

 8.7

 3.1

Anorectum (V_6500cGy)

Mean

7.0 ± 2.9

5.1 ± 2.5

6.4 ± 3.5

7.4 ± 4.9

5.5 ± 4.0

8.1 ± 6.5

7.4 ± 6.4

Range

2.8–14.4

1.8–9.3

2.4–15.3

0.1–22.8

0.1–17.0

0.0–28.9

0.0–27.1

Failure rate of uncertainty plans (%)

5.1

 0.3

 10.9

 8.6

Anorectum (V_8000cGy)

Mean

0.9 ± 1.1

0.5 ± 0.8

1.1 ± 1.8

1.4 ± 2.3

0.8 ± 1.5

1.8 ± 3.0

1.9 ± 3.4

Range

0.0–3.5

0.0–2.6

0.0–7.7

0.0–12.3

0.0–7.1

0.0–12.4

0.0–17.7

Failure rate of uncertainty plans (%)

0.6

 0

 3.0

 5.8

Bladder (V_4000cGy)

Mean

21.9 ± 11.4

13.7 ± 7.3

15.3 ± 7.7

21.9 ± 11.9

13.5 ± 7.8

21.9 ± 12.8

15.1 ± 9.3

Range

3.4–44.5

1.8–31.5

2.2–31.1

2.3–53.4

1.0–42.0

1.7–60.9

0.9–46.0

Failure rate of uncertainty plans (%)

1.1

 0.0

 1.7

 0.0

Bladder (V_6500cGy)

Mean

8.5 ± 4.7

6.0 ± 3.5

7.4 ± 3.9

8.6 ± 5.4

5.9 ± 4.4

8.7 ± 6.5

7.6 ± 5.9

Range

1.2–19.7

0.6–14.3

0.8–15.2

0.6–28.4

0.2–25.1

0.3–34.7

0.1–30.7

Failure rate of uncertainty plans (%)

1.1

 0.3

 2.3

 0.9

Bladder (V_8000cGy)

Mean

2.5 ± 2.3

0.6 ± 0.9

1.3 ± 1.3

2.7 ± 2.9

0.6 ± 1.2

2.9 ± 3.6

1.4 ± 2.1

Range

0.0–8.3

0.0–3.2

0.0–4.3

0.0–15.6

0.0–9.39

0.0–20.9

0.0–11.7

Failure rate of uncertainty plans (%)

2.4

0.0 

 4.8

 0.6