Palliative radiotherapy of bone metastases in octogenarians: How do the oldest olds respond? Results from a tertiary cancer center with 288 treated patients

Table 2 Treatment characteristics regarding palliative radiotherapy of spinal cord metastases of 288 octogenarian cancer patients

	n	%
Radiotherapy completion
Completed	249	86.5
Discontinued	39	13.5
Reason for discontinuation (n = 39)
Death during radiotherapy	19	48.7
Patient’s wish	5	12.8
Worsening of general condition	14	35.9
Unknown	1	2.6
Localization (n = 516)
Head-and-neck (w/o cervical spine)	15	2.9
Spine	254	49.2
Pelvis	153	29.7
Thorax (w/o thoracic spine)	37	7.2
Upper extremity	28	5.4
Lower extremity	29	5.6
SINS for spine metastases (n = 216)^a
0–6 (stable)	102	47.2
7–12 (possibly impending)	102	47.2
13–18 (unstable)	12	5.6
Mizumoto score for spine metastases (n = 216)^a
0–4	140	64.8
5–9	74	34.3
10–14	2	0.9
Orthopedic corset
No orthopedic corset	258	89.6
Orthopedic corset	30	10.4
Bone-modifying agents
No bone-modifying agents	161	55.9
Bisphosphonates	105	36.5
Denosumab	20	6.9
Unknown	2	0.7
Systemic anti-cancer treatment
No systemic treatment	209	72.6
Systemic treatment	77	26.7
Unknown	2	0.7

	Median	IQR
Radiotherapy fractionation (n = 516)
Number of fractions	12	10–14
Single dose [Gy]	3	2.5–3
Total dose [Gy]	35	30–35

IQR interquartile range, SINS Spinal Instability Neoplastic Score, w/o without
^aIf patients exhibited more than one irradiated spinal metastasis, the worst Mizumoto and SINS value is presented

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