Factor | Subgroup (n) | Maintaining ambulatory status, n (%) | p value |
---|---|---|---|
Age | ≤ 65 years (85) | 60 (71) | 0.74 |
> 65 years (85) | 58 (68) | ||
Interval FD to MSCC | ≤ 15 months (122) | 84 (69) | 0.80 |
> 15 months (48) | 34 (71) | ||
Visceral metastases | No (24) | 20 (83) | 0.15 |
Yes (146) | 98 (67) | ||
Further bone metastases | No (48) | 31 (65) | 0.39 |
Yes (122) | 87 (71) | ||
Primary tumor type | Breast cancer (26) | 15 (58) | 0.069 |
Prostate cancer (13) | 6 (46) | ||
Myeloma/lymphoma (9) | 8 (89) | ||
Lung cancer (59) | 46 (78) | ||
Other malignancies (63) | 43 (68) | ||
Sex | Female (58) | 39 (67) | 0.66 |
Male (112) | 79 (71) | ||
Time developing motor deficits | 0–7 days (58) | 33 (57) | < 0.001 |
8–14 days (51) | 32 (63) | ||
> 14 days (61) | 53 (87) | ||
ECOG performance score | 1–2 (69) | 59 (86) | < 0.001 |
3–4 (101) | 59 (58) | ||
Number of affected vertebrae | 1–2 (79) | 58 (73) | 0.29 |
≥ 3 (91) | 60 (66) | ||
Radiotherapy regimen | 1 × 8 Gy/5 × 4 Gy (71) | 50 (70) | 0.81 |
5 × 5 Gy/Longer-course RT (99) | 68 (69) | ||
Entire cohort | N = 170 | 118 (69) |