Fig. 5

Effects of PARP1 inhibitor on the expression of Ku70 and translocations in AHH-1 cell lines. A Representative images of the protein expression of PARP1 in cells treated with different dose X-rays. B The protein expression analysis (n = 3) of PARP1 in cells treated with different dose X-rays. C Representative images of the protein expression of PARP1 and Ku70 in cells treated with PARPi (Olaparib). D The protein expression analysis (n = 3) of PARP1 and Ku70 in cells treated with PARPi (Olaparib). E Representative images of the protein expression of PARP1 and Ku70 in cells treated with X-rays and in combination with PARPi (Olaparib). F The protein expression analysis (n = 3) of PARP1 and Ku70 in cells treated with X-rays and in combination with PARPi (Olaparib). G The protein expression of Ku70 (n = 3) in PBLs treated with X-rays alone (Olaparib⁻) and in combination with PARPi (Olaparib⁺). H The frequency of chromosome translocations (n = 3) in cells treated with X-rays alone (DMSO) and in combination with PARPi (Olaparib). *stands for that P < 0.05, **indicates that P < 0.01