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Table 1 Patient characteristics

From: Assessing radiation-induced carotid vasculopathy using ultrasound after unilateral irradiation: a cross-sectional study

Characteristic Patients scanned with Aixplorer system (n = 26)
Demographics
 Men, n (%) 12 (46)
 Median age, years [IQR] 40.5 [33.8–44.8]
 Median follow-up after RT, years [IQR] 7.2 [6.0–10.0]
Diagnosis, n (%)
 Carcinoma of parotid 6 (23)
 Pleiomorphic adenoma of parotid 8 (31)
 Carcinoma of oropharynx 2 (8)
 Malignant lymphoma 7 (27)
 Others 3 (12)
Chemotherapy, n (%)
 Anthracycline 7 (26)
 Platinum-based 1 (4)
 Alkylating 7 (26)
 Other 1 (4)
 Total 8 (31)
Surgery
 (Partial) parotidectomy 15 (58)
 Cervical lymph node dissection 5 (19)
 Partial glossectomy 2 (8)
 (Hemi)mandibulectomy 2 (8)
 Other 2 (8)
 Total 18 (69)
CVD risk factors, n (%)
 Smoking  
  - No 17 (65)
  - Current 4 (15)
  - Former 5 (19)
  - Pack years, median [IQR] 16.0 (9.5–27.0)
  Positive family history of CVD 7 (27)
  Chronic daily stress 8 (31)
  Hypertension 7 (27)
  Hypercholesterolemia 8 (38)
  Overweight 9 (39)
  Diabetes 1 (4)
  Renal insufficiency 3 (13)
Number of CVD risk factors, n (%)
 0 3 (12)
 1 6 (23)
 2 10 (39)
  ≥ 3 7 (27)
Radiation dose, Gy (median [IQR], min–max)
  Proximal CCA2 1 [0–31], 0–553
  Mid-CCA2 4 [1–30], 1–553
  Distal CCA2 22 [8–39], 1–55
  ICA2 43 [29–52], 1–59
 Total applied to the neck 50 [38–66], 30–1001
  1. RT radiotherapy, CVD cardiovascular disease, CCA common carotid artery, ICA internal carotid artery
  2. 1One patient underwent a re-irradiation for recurrence of the primary tumor resulting in a total dose of 100 Gy
  3. 2Carotid on irradiated side
  4. 3Patients with parotid gland tumors generally received low radiation doses in more proximal common carotid artery segments, but higher doses in the distal common carotid artery and internal carotid artery