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Table 1 Patient characteristics, tumor classification and treatment of all patients with recurrent head and neck cancer

From: Ways to unravel the clinical potential of carbon ions for head and neck cancer reirradiation: dosimetric comparison and local failure pattern analysis as part of the prospective randomized CARE trial

Pat

ReRT

Age (y)

KPS (%)

Localization

Type

Concept

T

N

M

R

G

Interval (y)

ReRT EQD2 (Gy)

Cum. EQD2 (Gy)

CTV (ccm)

01

CIRT

54

70

Oral cavity

SCC

Postop

4

0

0

2

2

1.0

75.0

129.0

167.9

02

CIRT

57

90

Nasopharynx

SCC

Def

2

0

0

 

2

0.7

63.8

137.8

30.6

03

CIRT

61

90

Hypopharynx

SCC

Def

4

0

0

 

3

3.6

63.8

123.8

84.0

04

VMAT

72

80

Sinuses

SCC

Def

4

0

0

 

2

1.0

60.0

126.0

110.0

05

CIRT

73

70

Oral cavity

MEC

Def

4

0

0

 

3

1.0

67.5

147.5

25.0

06

VMAT

71

80

Oropharynx

SCC

Def

4

0

0

 

2

7.2

60.0

123.0

65.0

07

VMAT

54

80

Nasopharynx

SCC

Def

1

2

0

 

3

4.5

60.0

124.0

54.7

08

CIRT

54

90

Sinuses

AC

Postop

3

0

0

2

3

1.6

67.5

127.5

49.3

09

VMAT

52

80

Skull base

AC

def

4

0

0

 

3

0.9

60.0

130.0

10.4

10

VMAT

49

80

Nasopharynx

SCC

def

4

0

0

 

3

3.3

60.0

124.0

31.7

11

VMAT

65

80

Nasal cavity

SCC

Def

3

0

0

 

3

4.0

60.0

130.0

37.4

12

VMAT

55

80

Nasal cavity

SCC

Postop

3

0

1

1

2

1.7

60.0

120.0

25.6

13

CIRT

62

70

Oral cavity

SCC

Def

3

0

0

 

2

8.3

63.8

137.8

42.4

14

CIRT

69

70

Oral cavity

SCC

Def

4

0

0

 

3

28.0

63.8

138.8

196.4

15

CIRT

50

90

Nasal cavity

SCC

Postop

4

0

0

2

3

1.2

63.8

129.8

139.6

16

CIRT

69

80

Oropharynx

SCC

Def

4

0

0

 

3

17.9

67.5

133.5

42.6

  1. CIRT carbon ion radiotherapy, VMAT volumetric modulated arc therapy, KPS Karnofsky Performance Score, EQD2 equivalent dose in 2 Gy fractions, ReRT re-radiotherapy, GTV gross tumor volume, CTV clinical target volume, PTV planning target volume, f female, m male, SCC squamous cell carcinoma, MEC mucoepidermoid carcinoma, AC adenocarcinoma