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Table 2 Univariate analysis of PFS and OS in gallbladder cancer

From: Postoperative recurrent patterns of gallbladder cancer: possible implications for adjuvant therapy

Characteristics No Percentage (%) Median DFS P value Median OS P value
Gender Male 37 33.9 Not reached 0.5023 Not reached 0.396
Female 72 66.1 36 41
Age (yrs)  < 65 years old 53 48.6 Not reached 0.6539 Not reached 0.0707
 ≥ 65 years old 56 51.4 24 32
CA199 (107 cases)  > 37 U/ml 52 48.6 8 0.0002 22 0.0029
Normal 55 51.4 Not reached Not reached
CEA (105 cases)  > 5 ng/ml 26 24.8 10 0.0009 20.5 0.0064
Normal 79 75.2 Not reached Not reached
Gallstone Positive 61 56.0 64 0.6478 37 0.5273
Negative 48 44.0 39.5 Not reached
Bile duct stone Positive 20 18.3 Not reached 0.0778 Not reached 0.3589
Negative 89 81.7 30 42
Hepatitis Positive 5 4.6 5 0.5023 15 0.3835
Negative 104 95.4 64 Not reached
Hypertension Positive 37 33.9 42 0.8149 44 0.6685
Negative 72 66.1 64 Not reached
Diabetes Positive 7 6.4 Not reached 0.7271 Not reached 0.3616
Negative 102 93.6 48 42
Schistosomiasis Positive 5 4.6 Not reached 0.3306 Not reached 0.7756
Negative 104 95.4 48 44
Jaundice Serum bilirubin > 17.1 μmol/L 29 26.6 Not reached 0.5973 32 0.3446
Normal 80 73.4 48 Not reached
T stage Tis + T1 16 14.7 Not reached  < 0.0001 Not reached  < 0.0001
T2 50 45.9 Not reached Not reached
T3 35 32.1 6 18
T4 8 7.3 3 11
N stage N0 67 61.5 Not reached  < 0.0001 Not reached  < 0.0001
N1 26 23.9 12 18
N2 16 14.7 5 11
TNM Staging II 31 28.4 Not reached  < 0.0001 Not reached  < 0.0001
III 36 33.0 22 24
IV 26 23.9 4 13
Liver invasion Positive 30 27.5 3  < 0.0001 11  < 0.0001
Negative 79 72.5 Not reached Not reached
Perineural invasion Positive 33 30.3 15 0.0412 24 0.0169
Negative 76 69.7 Not reached Not reached
Lymphovascular invasion Positive 36 33.0 9 0.0004 20 0.0003
Negative 73 67.0 Not reached Not reached
Tumor differentiation Well 20 18.3 Not reached 0.0006 Not reached 0.0002
Moderate 35 32.1 64 Not reached
Poor + Undifferentiated 46 42.2 6 15
  1. The bold figures in the table are the data with P < 0.05