Table 2 Univariate analysis of PFS and OS in gallbladder cancer
From: Postoperative recurrent patterns of gallbladder cancer: possible implications for adjuvant therapy
Characteristics | No | Percentage (%) | Median DFS | P value | Median OS | P value | |
|---|---|---|---|---|---|---|---|
Gender | Male | 37 | 33.9 | Not reached | 0.5023 | Not reached | 0.396 |
Female | 72 | 66.1 | 36 | 41 | |||
Age (yrs) |  < 65 years old | 53 | 48.6 | Not reached | 0.6539 | Not reached | 0.0707 |
 ≥ 65 years old | 56 | 51.4 | 24 | 32 | |||
CA199 (107 cases) |  > 37 U/ml | 52 | 48.6 | 8 | 0.0002 | 22 | 0.0029 |
Normal | 55 | 51.4 | Not reached | Not reached | |||
CEA (105 cases) |  > 5 ng/ml | 26 | 24.8 | 10 | 0.0009 | 20.5 | 0.0064 |
Normal | 79 | 75.2 | Not reached | Not reached | |||
Gallstone | Positive | 61 | 56.0 | 64 | 0.6478 | 37 | 0.5273 |
Negative | 48 | 44.0 | 39.5 | Not reached | |||
Bile duct stone | Positive | 20 | 18.3 | Not reached | 0.0778 | Not reached | 0.3589 |
Negative | 89 | 81.7 | 30 | 42 | |||
Hepatitis | Positive | 5 | 4.6 | 5 | 0.5023 | 15 | 0.3835 |
Negative | 104 | 95.4 | 64 | Not reached | |||
Hypertension | Positive | 37 | 33.9 | 42 | 0.8149 | 44 | 0.6685 |
Negative | 72 | 66.1 | 64 | Not reached | |||
Diabetes | Positive | 7 | 6.4 | Not reached | 0.7271 | Not reached | 0.3616 |
Negative | 102 | 93.6 | 48 | 42 | |||
Schistosomiasis | Positive | 5 | 4.6 | Not reached | 0.3306 | Not reached | 0.7756 |
Negative | 104 | 95.4 | 48 | 44 | |||
Jaundice | Serum bilirubin > 17.1 μmol/L | 29 | 26.6 | Not reached | 0.5973 | 32 | 0.3446 |
Normal | 80 | 73.4 | 48 | Not reached | |||
T stage | Tis + T1 | 16 | 14.7 | Not reached |  < 0.0001 | Not reached |  < 0.0001 |
T2 | 50 | 45.9 | Not reached | Not reached | |||
T3 | 35 | 32.1 | 6 | 18 | |||
T4 | 8 | 7.3 | 3 | 11 | |||
N stage | N0 | 67 | 61.5 | Not reached |  < 0.0001 | Not reached |  < 0.0001 |
N1 | 26 | 23.9 | 12 | 18 | |||
N2 | 16 | 14.7 | 5 | 11 | |||
TNM Staging | II | 31 | 28.4 | Not reached |  < 0.0001 | Not reached |  < 0.0001 |
III | 36 | 33.0 | 22 | 24 | |||
IV | 26 | 23.9 | 4 | 13 | |||
Liver invasion | Positive | 30 | 27.5 | 3 |  < 0.0001 | 11 |  < 0.0001 |
Negative | 79 | 72.5 | Not reached | Not reached | |||
Perineural invasion | Positive | 33 | 30.3 | 15 | 0.0412 | 24 | 0.0169 |
Negative | 76 | 69.7 | Not reached | Not reached | |||
Lymphovascular invasion | Positive | 36 | 33.0 | 9 | 0.0004 | 20 | 0.0003 |
Negative | 73 | 67.0 | Not reached | Not reached | |||
Tumor differentiation | Well | 20 | 18.3 | Not reached | 0.0006 | Not reached | 0.0002 |
Moderate | 35 | 32.1 | 64 | Not reached | |||
Poor + Undifferentiated | 46 | 42.2 | 6 | 15 | |||