Table 1 Inclusion and exclusion criteria
From: Preoperative hypofractionated radiotherapy for soft tissue sarcomas: a systematic review
Category | Inclusion criteria | Exclusion criteria |
|---|---|---|
Study design | Any except narrative reviews and systematic reviews | Systematic reviews Narrative reviews |
Population | Age: ≥ 18 years | Pediatric patients (< 18 years) |
| Â | Sex: Any | Retroperitoneal sarcoma |
| Â | Race: Any | Â |
| Â | Disease: Soft tissue sarcomas located at the extremities and/or trunk | Other location than extremity or trunk |
| Â | Histological grade: Any | Â |
| Â | Stage: Localized | Â |
Intervention | Hypofractionated RT (> 2.2 Gy/fraction/day) Neoadjuvant RT Neoadjuvant and/or adjuvant chemotherapy Surgical resection | Normofractionated RT (1.8–2.2 Gy/fraction) Hyperfractionated RT (< 1.8 Gy/fraction) Hyperthermia Postoperative RT (trials adding postoperative boost to preoperative RT were not excluded) |
Outcomes | Acute toxicity including wound complications Late toxicity OS DFS LC LR LRFS |  |
Date range | Until November 30th, 2021 | Â |