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Table 1 Demographic and clinical characteristics of the patients (N = 1355)

From: Association of neutrophil-to-lymphocyte ratio, radiotherapy fractionation/technique, and risk of development of distant metastasis among patients with locally advanced rectal cancer

Variables

N

%

Age, years

 Mean (SD)

59.7

SD 12.0

 < 60

667

49.2

 ≥ 60

688

50.8

Sex

 Female

475

35.1

 Male

880

64.9

Clinical T stage

 Tis-T2

131

9.7

 T3/4

1211

89.4

 Tx

13

1.0

Clinical N stage

 N0

252

18.6

 N1/2

1049

77.4

 Nx

54

4.0

Distance of tumor from the anal verge

 Lower

559

41.3

 Middle

675

49.8

 Upper

121

8.9

Year of diagnosis*

 < 2013

511

37.7

 ≥ 2013

844

62.3

ypT

 Tis/0

286

21.1

 T1/2

381

28.1

 T3/4

682

50.3

 Tx

6

0.4

ypN

 N0

980

72.3

 N1/2

372

27.5

 Nx

3

0.2

Neoadjuvant chemotherapy

 Capecitabine

794

58.6

 FL

422

31.1

 Others

139

10.3

Adjuvant chemotherapy

 FL

277

20.4

 Capecitabine

230

17.0

 FOLFOX

204

15.1

 Others

16

1.2

 None

628

46.3

RT modality

 3D-CRT

851

62.8

 Tomotherapy

504

37.2

RT fractionation

 LCRT

1325

97.8

 SCRT

30

2.2

  1. SD standard deviation, FL fluorouracil, 3D-CRT three-dimensional conformal radiotherapy, LCRT long-course RT, SCRT short-course RT
  2. *Colorectal cancer multidisciplinary team was implemented in the year 2012–2013 at our institution