Table 1 patient characteristics
Characteristic | No. of patients (%), n = 201 | Tübingen cohort (%), n = 126 | Florence cohort (%), n = 75 | p value |
|---|---|---|---|---|
Median age | ||||
years (IQR) | 65 (56–72) | 63 (53.7–71.2) | 67 (58–74) | 0.041 |
Sex | Â | Â | Â | Â |
Male | 133 (66.1%) | 81 (64.3%) | 52 (69.3%) | 0.538 |
Female | 68 (33.9%) | 45 (35.7%) | 23 (30.7%) | Â |
Staging (TNM/AJCC 7th ed.) | ||||
cT2N1/N2 | 11 (5.5%) | 7 (5.5%) | 4 (5.3%) | 0.655 |
cT3N0 | 41 (20.4%) | 22 (17.5%) | 19 (25.3%) | |
cT3N1/N2 | 127 (63.2%) | 81 (64.3%) | 46 (61.4%) | |
cT4anyN | 22 (10.9%) | 16 (12.7%) | 6 (8%) | |
Primary location | ||||
Low rectum | 89 (44.3%) | 50 (39.7%) | 39 (52%) | 0.148 |
Middle rectum | 101 (50.2%) | 70 (55.5%) | 31 (41.3%) | |
High rectum | 11 (5.5%) | 6 (4.8%) | 5 (6.7%) | |
Median time interval (end of RT- surgery) weeks (IQR) | 7 (6–9) | 6 (5–7) * | 9 (8–11) |  < 0.0001 |