Table 6 Previous studies of late radiation pneumonitis in patients with interstitial pneumonitis
From: Outcomes of proton therapy for non-small cell lung cancer in patients with interstitial pneumonia
References | Treatment | Number of patients | Median total dose (Gy) | Dose per fraction (Gy) | Pneumonitis | |
|---|---|---|---|---|---|---|
Grade 3 | Grade 4/5 | |||||
Lee et al. [8] | 3D-CRT | 15 | 56.9 | 1.8–2.0 | 6 (40%) | 5 (33%) |
Yamashita et al. [9] | SBRT | 13 | 48 | 12 | N/A | 7 (54%) |
Tsurugai et al. [36] | SBRT | 42 | 40–60 | 8–22 | 4 (9.5%) | 1 (2.4%) |
Ono et al. [37] | PT | 16 | 80 (RBE) | 3.2 (RBE) | 1 (6.3%) | 1 (6.3%) |
Present study | PT | 29 | 66–74 (RBE) | 6.6–2.0 (RBE) | 2 (6.9%) | 0 (0%) |