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Fig. 1 | Radiation Oncology

Fig. 1

From: Molecular features of glioblastomas in long-term survivors compared to short-term survivors—a matched-pair analysis

Fig. 1

a Overall survival function comparing MGMT promoter methylated tumors with unmethylated tumors. Hypermethylation of the MGMT promoter region was associated with an increase in OS (p = 0.0012). Survival in both groups is longer compared to an unselected group of GB patients due to the artificially high number of long-term survivors (55 patients; 37.4%). All patients with available MGMT data are Included in this graph (n = 147). b Overall survival function comparing tumors which were at least partially negative for GFAP with tumors in which samples stained positive for GFAP. The difference between the groups was significant (p = 0.0022). As in a, survival in both groups is longer compared to an unselected group of GB patients due to the artificially high number of long-term survivors (72 patients; 34.3%). All patients with available GFAP data are included in this graph (n = 210)

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