Skip to main content

Table 3 Incidence of AEs

From: Therapeutic effect of osimertinib plus cranial radiotherapy compared to osimertinib alone in NSCLC patients with EGFR-activating mutations and brain metastases: a retrospective study

Treatment-related AEs, n (%)

Osimertinib group

(n = 40)

Osimertinib + RT group

(n = 21)

P

Any grade

13 (32.5)

10 (47.6)

0.762

Fatigue

1 (2.5)

0 (0)

 

Rash

5 (12.5)

1 (4.7)

 

Diarrhea

3 (7.5)

1 (4.7)

 

Myocardial damage

2 (5.0)

0 (0)

 

Pneumonitis

3 (7.5)

0 (0)

 

Oral ulcer

0 (0)

1 (4.7)

 

Leukoencephalopathy

0 (0)

6 (28.5)

 

Neutrophil count decreased

6 (15.0)

3 (14.2)

 

Grade ≥ 3

3 (7.5)

4 (19.0)

0.220

Neutrophil count decreased

3 (7.5)

1 (4.7)

 

Leukoencephalopathy

0

3 (14.2)

 
  1. RT cranial radiotherapy