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Table 1 Demographic and clinical characteristics of patients with neuroblastoma, SEER 18

From: Risk of developing second malignant neoplasms in patients with neuroblastoma: a population study of the US SEER database

Variables

Categories

Cohort (%)

All NB patients (n = 4338)

SMN (n = 38)

Sex

Male

2294 (52.9)

19 (50.0)

Female

2044 (47.1)

19 (50.0)

Age at diagnosis (first primary) (years)

< 1

1493 (34.4)

14 (36.8)

1–5

2347 (54.1)

18 (47.4)

6–19

498 (11.5)

6 (15.8)

Year of diagnosis

1973–1979

303 (7.0)

5 (13.2)

1980–1989

506 (11.7)

18 (47.4)

1990–1999

750 (17.3)

5 (13.2)

2000–2009

1739 (40.1)

9 (23.7)

2010–2015

1040 (24.0)

1 (2.6)

Primary Site

Abdomen

3019 (70.7)

24 (63.2)

Thorax

773 (18.1)

10 (26.3)

Others

478 (11.2)

4 (10.5)

Histologic type

Neuroblastoma, NOS

3667 (84.5)

36 (94.7)

Ganglioneuroblastoma

671 (15.5)

2 (5.3)

Race

White

3410 (79.6)

30 (78.9)

Black

528 (12.3)

5 (13.2)

Other

348 (8.1)

3 (7.9)

Radiotherapy

Yes

1085 (25.0)

19 (50.0)

No/unknown

3253 (75.0)

19 (50.0)

Chemotherapy

Yes

2829 (65.2)

28 (73.7)

No/unknown

1509 (34.8)

10 (26.3)

  1. SEER 18, surveillance, epidemiology, and end results program 18; NB, Neuroblastoma; SMN, second malignant neoplasm; NOS, not otherwise specified