Table 3 Overview over quantities related to the effect of hypoxia in the primary CTV and hypoxic volume for each patient
Patient | Dose to PTV [GyRBE] | Volume of GTVhypoxic [cc] | DE | LETd in CTVprim [keV/µm] | pO2 in GTVhypoxic [mmHg] | pO2 in CTVprim – GTVhypoxic [mmHg] | OER in GTVhypoxic | OER in CTVprim-GTVhypoxic |
|---|---|---|---|---|---|---|---|---|
1 | 60 | 48.3 | 1.17 | 2.2 (2.0,2.4) | 5.4 (4.5,6.6) | 29.5 (12.9,30) | 1.22 (1.18,1.27) | 1.0 (1.0,1.08) |
2 | 70 | 58.9 | 1.15 | 2.3 (2.2,2.6) | 6.0 (5.3,6.9) | 25.1 (11.9,30) | 1.2 (1.17,1.23) | 1.0 (1.0,1.08) |
3 | 70 | 19.8 | 1.10 | 1.9 (1.6,2.3) | 7.9 (7.0,8.7) | 30.0 (23.3,30) | 1.15 (1.13,1.17) | 1.0 (1.0,1.02) |
4 | 70 | 37.5 | 1.13 | 2.1 (1.9,2.4) | 6.6 (6.0,7.2) | 30.0 (15.7,30) | 1.18 (1.16,1.2) | 1.0 (1.0,1.05) |
5 | 70 | 8.0 | 1.12 | 2.6 (2.4,2.9) | 7.2 (6.1,8.4) | 30.0 (19.0,30) | 1.16 (1.13,1.2) | 1.0 (1.0,1.03) |
6 | 70 | 52 | 1.22 | 2.5 (2.0,3.0) | 5.0 (3.5,6.4) | 29.2 (14.3,30) | 1.24 (1.19,1.34) | 1.0 (1.0,1.06) |
7 | 70 | 46.8 | 1.10 | 1.9 (1.7,2.1) | 8.2 (6.8,9.3) | 30.0 (30,30) | 1.14 (1.12,1.17) | 1.0 (1.0,1.0) |
8 | 60 | 23.3 | 1.07 | 2.2 (2.0,2.4) | 9.2 (8.3,10.5) | 30.0 (30,30) | 1.12 (1.1,1.14) | 1.0 (1.0,1.0) |
9 | 70 | 20.9 | 1.13 | 2.2 (1.9,2.6) | 6.7 (6.2,7.2) | 28.0 (12.7,30) | 1.18 (1.16,1.19) | 1.0 (1.0,1.07) |
10 | 70 | 5.2 | 1.12 | 2.6 (2.2,3.2) | 7.4 (6.3,8.4) | 30.0 (19.9,30) | 1.16 (1.13,1.19) | 1.0 (1.0,1.03) |
Cohort Median | 70 | 30.4 | 1.13 | 2.2 | 7 | 30 | 1.17 | 1 |