Table 1 Patient baseline characteristics by local treatment groups
Variables | n | Surgery alone (%) | RT alone (%) | Surgery + RT (%) | P |
|---|---|---|---|---|---|
Age (years) | |||||
65–69 | 6852 | 2424 (34.1) | 2371 (47.0) | 2057 (43.1) | < 0.001 |
70–74 | 4652 | 1912 (26.9) | 1430 (28.4) | 1310 (27.5) | |
≥ 75 | 5419 | 2774 (39.0) | 1240 (24.6) | 1405 (29.4) | |
Gender | |||||
Male | 11,380 | 4129 (58.1) | 4009 (79.5) | 3242 (67.9) | < 0.001 |
Female | 5543 | 2981 (41.9) | 1032 (20.5) | 1530 (32.1) | |
Race/ethnicity | |||||
Non-Hispanic White | 13,518 | 5866 (82.5) | 3903 (77.4) | 3749 (78.6) | < 0.001 |
Non-Hispanic Black | 1056 | 294 (4.1) | 434 (8.6) | 328 (6.9) | |
Hispanic (all races) | 1197 | 473 (6.7) | 366 (7.3) | 358 (7.5) | |
Other | 1049 | 414 (5.8) | 310 (6.1) | 325 (6.8) | |
Unknown | 103 | 63 (0.9) | 28 (0.6) | 12 (0.3) | |
Grade | |||||
Well differentiated | 3256 | 2095 (29.5) | 508 (10.1) | 653 (13.7) | < 0.001 |
Moderately differentiated | 6139 | 2571 (36.2) | 1827 (36.2) | 1741 (36.5) | |
Poorly/undifferentiated | 3605 | 742 (10.4) | 1415 (28.1) | 1448 (30.3) | |
Unknown | 3923 | 1702 (23.9) | 1291 (25.6) | 930 (19.5) | |
Histology | |||||
Squamous histology | 14,031 | 5584 (78.5) | 4806 (95.3) | 3641 (76.3) | < 0.001 |
Non-squamous histology | 2892 | 1526 (21.5) | 235 (4.7) | 1131 (23.7) | |
SEER stage | |||||
Localized | 9869 | 5586 (78.6) | 2124 (42.1) | 2159 (45.2) | < 0.001 |
Regional | 5479 | 1110 (15.6) | 2282 (45.3) | 2087 (43.7) | |
Distant | 1111 | 176 (2.5) | 488 (9.7) | 447 (9.4) | |
Unknown | 464 | 238 (3.3) | 147 (2.9) | 79 (1.7) | |
Tumor location | |||||
Oral cavity | 5966 | 3405 (47.9) | 1291 (25.6) | 1270 (26.6) | < 0.001 |
Oropharynx | 1566 | 195 (2.7) | 761 (15.1) | 610 (12.8) | |
Nasopharynx | 361 | 19 (0.3) | 80 (5.6) | 62 (1.3) | |
Hypopharynx | 338 | 37 (0.5) | 232 (4.6) | 69 (1.4) | |
Nasal cavity and sinus | 747 | 309 (4.3) | 98 (1.9) | 340 (7.1) | |
Salivary gland | 1772 | 761 (10.7) | 22 (0.4) | 989 (20.7) | |
Larynx | 4471 | 856 (21.5) | 2273 (45.1) | 1342 (28.1) | |
Other | 1702 | 1528 (12.0) | 84 (1.7) | 90 (1.9) | |
Chemotherapy | |||||
No | 12,949 | 7040 (99.0) | 2369 (47.0) | 3540 (74.2) | < 0.001 |
Yes | 3974 | 70 (1.0) | 2672 (53.0) | 1232 (25.8) | |
Marital status | |||||
Married | 10,397 | 4108 (57.8) | 3211 (63.7) | 3078 (64.5) | < 0.001 |
Divorce | 1395 | 484 (6.8) | 514 (10.2) | 397 (8.3) | |
Single | 1559 | 600 (8.4) | 506 (10.0) | 453 (9.5) | |
Widowed | 2308 | 1114 (15.7) | 548 (10.9) | 646 (13.5) | |
Unknown | 1264 | 804 (11.3) | 262 (5.2) | 198 (4.1) | |