Table 4 Summary of studies on intra-fractional variation of OARs
From: Intra-fractional dosimetric analysis of image-guided intracavitary brachytherapy of cervical cancer
| Â | Nesvacil 2013 [14] | Miyasaka 2020 [12] | Yan 2021 | Nomden 2014 [13] | Simha 2014 [15] |
|---|---|---|---|---|---|
Image | MRI & CT | CT | CT & CBCT | MRI | MRI & CT |
Fraction | 4F | 6 Gy | 6 Gy × 5F | 7 Gy × 4F | 7 Gy × 4F |
Interval | 3–5 h | 43 min | 53 min | 3.9 h (2.8–5.5) | 2 h (0.5–3.5) |
D90 HRCTV |  − 2.5% ± 10.8% | – |  − 1.2 ± 4.5% |  − 0.1 ± 0.5 Gy | – |
D2cc Bladder | 1.3% ± 17.7% | 2.4 ± 8.8% |  − 0.6 ± 17.1% | 0.1 ± 1.1 Gy | 0.5 ± 0.4 Gy |
D2cc Rectum | 3.8% ± 20.5% |  − 2.3 ± 9.9% | 9.3 ± 14.6% | 0.4 ± 1.5 Gy | 0.3 ± 0.3 Gy |
D2cc Sigmoid |  − 2.3% ± 23.5% | – | 7.15 ± 20.5% | 0.4 ± 1.2 Gy | 0.6 ± 0.6 Gy |