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Table 4 Acute and late toxicities

From: Clinical outcomes and patterns of failure of head and neck mucosal melanoma treated with multiple treatment modalities

Event Grades 1–2 Grade 3–4
Acute toxicities   
Hematological   
 Anemia 84 (32.1%) 14 (5.3%)
 Thrombocytopenia 9 (3.4%) 2 (0.8%)
 Leucopenia 23 (8.8%) 5 (1.9%)
 Neutropenia 18 (6.9%) 6 (2.3%)
Nonhematological   
 Dermatitis 60 (22.9%) 4 (1.5%)
 Mucositis 42 (16.0% 8 (3.1%)
 Dry mouth 16 (6.1%) 4 (1.5%)
 Nausea 46 (17.6%) 9 (3.4%)
 Vomiting 41 (15.6%) 0
 Keratitis 2 (7.7%) 0
Late toxicities   
Hematological   
 Anemia 34 (13.0%) 4 (1.5%)
 Thrombocytopenia 2 (0.8%) 0
 Leucopenia 13 (5.0%) 0
 Neutropenia 11 (4.2%) 2 (0.8%)
Nonhematological   
 Nausea 28 (10.7%) 5 (1.9%)
 Vomiting 18 (6.9%) 2 (0.8%)
 Mucositis 26 (9.9%) 4 (1.5%)
 Nephrotoxicity 8 (3.1%) 1 (0.8%)
 Hepatitis 7 (2.7%) 2 (0.8%)
 Neurotoxicity 4 (1.5%) 0
 Cervical fibrosis 2 (0.8%) 0