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Table 3 Association of symptomatic radiation pneumonitis and RGS assessed on computed tomography scans performed one month after thoracic radiation therapy

From: High-dose thoracic radiation therapy for non-small cell lung cancer: a novel grading scale of radiation-induced lung injury for symptomatic radiation pneumonitis

Occurrence of symptomatic RP CTCAE grade ≥ 2

  

Fisher’s exact test

 

RGS grade 0–1 (n = 29)

RGS grade 2–3(n = 10)

 

RP – (n = 17)

17

0

RR 2.4, 95%CI 1.6–3.7, p < 0.01

RP + (n = 22)

12

10

 

Onset of symptomatic RP within 8 weeks after RT (n = 22)

 

RGS grade 0–1 (n = 12)

RGS grade 2–3 (n = 10)

 

Days, median (range)

104 (55–166)

42 (24–111)

RR 4.8, 95%CI 1.3–17.6, p < 0.01

 ≥ 8 weeks

10

2

 

 < 8 weeks

2

8

 
  1. RGS, radiation-induced lung injury grading scale; RP, radiation pneumonitis; CTCAE, Common Terminology Criteria for Adverse Events; RT, radiation therapy; RR, risk ratio