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Table 3 Association of symptomatic radiation pneumonitis and RGS assessed on computed tomography scans performed one month after thoracic radiation therapy

From: High-dose thoracic radiation therapy for non-small cell lung cancer: a novel grading scale of radiation-induced lung injury for symptomatic radiation pneumonitis

Occurrence of symptomatic RP CTCAE grade ≥ 2    Fisher’s exact test
  RGS grade 0–1 (n = 29) RGS grade 2–3(n = 10)  
RP – (n = 17) 17 0 RR 2.4, 95%CI 1.6–3.7, p < 0.01
RP + (n = 22) 12 10  
Onset of symptomatic RP within 8 weeks after RT (n = 22)
  RGS grade 0–1 (n = 12) RGS grade 2–3 (n = 10)  
Days, median (range) 104 (55–166) 42 (24–111) RR 4.8, 95%CI 1.3–17.6, p < 0.01
 ≥ 8 weeks 10 2  
 < 8 weeks 2 8  
  1. RGS, radiation-induced lung injury grading scale; RP, radiation pneumonitis; CTCAE, Common Terminology Criteria for Adverse Events; RT, radiation therapy; RR, risk ratio