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Table 1 The target and the OARs constraint functions and dosimetric evaluation metrics

From: The dosimetric impact of deep learning-based auto-segmentation of organs at risk on nasopharyngeal and rectal cancer

Site

Target/OARs

Prescription

Constraints or objectives

Dosimetric evaluation

NPC

PTV70.4

70.4 Gy/32 F

D95 > Prescription, D2 < 110% Prescription, uniform dose = Prescription

V100, D95, D2

PTV66

66 Gy/32 F

PTV60

60 Gy/32 F

PTV54

54 Gy/32 F

Eyes

/

Max Dose < 50 Gy

Max Dose

Lens

/

Max Dose < 25 Gy

Max Dose

Brainstem

/

Max Dose < 54 Gy

Max Dose

Temporal lobes

/

Max Dose < 65 Gy, V60 < 1%

Max Dose

Spinal cord

/

Max Dose < 45 Gy

Max Dose

Optic nerves

/

Max Dose < 54 Gy

Max Dose

Larynx

/

Mean Dose < 45 Gy

Mean Dose

Parotid

/

Mean Dose < 26 Gy

Mean Dose, V30

Oral cavity

/

Mean Dose < 40 Gy

Mean Dose

Temporomandibular joints

/

Max Dose < 70 Gy

Not evaluated

Chiasm

/

Max Dose < 54 Gy

Not evaluated

Rectum

PTV

50 Gy/25 F

D95 > Prescription, D2 < 110% Prescription, uniform dose = Prescription

V100, D95, D2

Femoral heads

/

V40 < 40%, Max Dose < 50 Gy

Mean Dose

Bladder

/

V40 < 50%

Mean Dose, V40