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Table 2 Cox model analysis for 125 patients local recurrent esophageal squamous cell carcinoma following radical (chemo) radiotherapy

From: A re-irradiation dose of 55–60 Gy improves the survival rate of patients with local recurrent esophageal squamous cell carcinoma after radiotherapy

Variables

Number

Univariate

Multivariate

HR

95%CI

P

HR

95%CI

P

Gender

 

0.758

0.505–1.138

0.181

   

Male

84

      

Female

41

      

Age (years)

 

1.519

1.046–2.208

0.028

1.472

1.010–2.144

0.044

 < 70

71

      

 ≥ 70

54

      

ECOG

 

1.593

1.004–2.527

0.048

1.641

1.027–2.621

0.038

0–1

102

      

2

23

      

Recurrence pattern

 

1.149

0.915–1.444

0.232

   

PR

67

      

LNR

25

      

PR + LNR

33

      

Time to recurrence (months)

 

0.507

0.346–0.745

0.001

0.484

0.328–0.713

< 0.001

 ≤ 24

68

      

 > 24

57

      

Chemotherapy

 

0.758

0.526–1.094

0.139

   

Yes

61

      

No

64

      

Re-irradiation dose

 

0.626

0.432–0.908

0.013

0.638

0.439–0.927

0.018

50–54 Gy

58

      

55–60 Gy

67

      
  1. HR Hazard ratio, 95%CI 95% confidence interval, ECOG Eastern Cooperative Oncology Group Performance Status, PR primary recurrence, LNR local lymph node recurrence