Table 3 Univariate and multivariable Cox analysis of prognostic factors for overall survival and progression free survival in 72 patients with unresectable sigmoid colon cancer (LASCC) treated with neoadjuvant chemoradiotherapy and surgery

Overall survival variable

R0 resection (R0 vs. non-R0)

0.292 (0.184–0.465)

0.973

0.937  (0.020–42.855)

pCR (pCR vs. non-pCR)

2.342 (0.690–7.946)

0.339

0.194  (0.007–5.597)

Down T stage (yes vs. non)

3.031 (1.033–8.894)

0.426

2.021 (0.358–11.419)

pN Stage group (pN0 vs. pN1)

5.234 (1.105–24.800)

0.601

2.845 (0.057-142.977)

pT Stage group (pT0-T3 vs. pT4a-4b)

2.678 (1.144–6.272)

0.634

0.659 (0.118–3.664)

Differentiation

0.062 (0.012–0.319)

0.003

36.443 (3.500–379.429)

PNI (yes vs. non)

4.138 (1.377–12.435)

0.875

1.205 (0.119–12.166)

Progress-free survival variable

R0 resection (R0 vs. non-R0)

0.343 (0.219–0.538)

0.232

0.091 (0.002–4.629)

pCR (pCR vs. non-pCR)

3.697 (0.865–15.806)

0.991

497,046.093 (0.000–infinity)

Down T stage (yes vs. non)

4.109 (1.490–11.333)

0.027

6.095 (1.228–30.253)

pT Stage group (pT0-T3 vs. pT4a-4b)

2.988 (1.293–6.907)

0.797

0.818 (0.177–3.786)

Differentiation

2.292  (0.827–6.356)

0.130

4.246 (0.653–27.599)

PNI  (yes vs. non)

3.883 (1.300-11.597)

0.251

3.108 (0.448–21.581)