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Table 2 Apical lesion patient characteristics

From: Estimating the tolerance of brachial plexus to hypofractionated stereotactic body radiotherapy: a modelling-based approach from clinical experience

 

Indiana University

Karolinska University

Total

Number of patients

37

52

89

Gender

 Male

21

23

44

 Female

16

29

45

Age at treatment, median (range)

73 (57–81)

72 (35–88)

 

Number of tumors

37

56

93

Primary lung cancer (NSCLC)

37

30a

67

Metastases

0

22

22

Tumors

 Right

21

28

49

 Left

16

28

44

Volume cc, median (range)

GTV 13 (1–113)

CTV 9.1 (0.10–74.5)

 

Follow-up months, median (range)

13 (1–71)

30 (6.1–72.2)

 

Total treatment dose (Gy), median (range)

57 (30–72)

Median 45 Gy in 3 fx

BED10 Range: 95–138 Gy

 

Median dose per fraction (Gy) (range)

19 (10–24)

15 (6–17)

 

Median number of fractions (range)

3 (3–4)

3 (3–10)

 

Number of patients with brachial plexopathy

 Total

7

7

14

 Grade 2

4

3

7

 Grade 3

2

4

6

 Grade 4

1

0

1

Brachial plexopathy development in months post-SBRT, median (range)

7 (6–23)

5.8 (0.7–13)

 
  1. NSCLC non-small cell lung cancer, GTV gross tumor volume, CTV clinical tumor volume, fx fractions; BED10 biological effective dose with α/β = 10 Gy
  2. aOne patient with metastasis later on