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Table 3 Biological equivalent dose (BED) and equivalent dose in 2 Gy per fraction (EQD2) for various SRS/HSRT radiation schedules

From: Current status and recent advances in resection cavity irradiation of brain metastases

Dose regimen

BED Gy10 (Tumor)

EQD10/2

BED Gy2 (Brain Parenchyma)

EQD2/2

30 Gy/5 fractions

48

40

120

60

25 Gy/5 fractions

37.5

31.25

87.5

43.75

27 Gy/3 fractions

51.3

42.75

148.5

74.25

24 Gy/3 fractions

43.2

36

120

60

20 Gy/1 fraction

60

50

220

110

18 Gy/1 fraction

50.4

42

180

90

16 Gy/1 fraction

41.6

34.67

144

72

14 Gy/1 fraction

33.6

28

112

56

12 Gy/ 1 fraction

26.4

22

84

42

  1. BED Gy10, biological equivalent dose with an α/β ratio of 10 Gy; BED Gy2, biological equivalent dose with an α/β ratio of 2 Gy; EQD10/2, eqivalent dose in 2 Gy/fractions with a BED Gy10; EQD2/2, eqivalent dose in 2 Gy/fractions with a BED Gy2; SRS, stereotactic radiosurgery; HSRT, hypofractionated stereoactic radiation therapy