From: MR-guided stereotactic body radiation therapy for primary cardiac sarcomas
Patient 1 (LMU) | Patient 2 (LMU) | Patient 3 (LMU) | Patient 4 (A. Gemelli) | |
---|---|---|---|---|
Histology | Fibroblastic/myofibroblastic sarcoma, G1 | Pleomorphic cardiac sarcoma, G3 | Biphasic synovial sarcoma, G2 | Pleomorphic cardiac sarcoma, G3 |
Localization | Left atrium | Right atrium | Epicardial right (3 lesions) | Right atrium/ventricle |
Age at time of treatment (years) | 49 | 80 | 61 | 66 |
Gender | Female | Female | Female | Male |
Karnofsky score (KPS) | 90 | 60 | 80 | 60 |
Symptoms before treatment | Fatigue CTCAE °1 | Fatigue CTCAE °1 dyspnea CTCAE °1 | Fatigue CTCAE °1 chest pain CTCAE °1 | Fatigue CTCAE °1 dyspnea CTCAE °2 |
Prior surgery | Yes; R1 | Yes; R2 | Yes, R0 (close) | Yes, R2 |
Time interval surgery to RT (months) | 7 | 1 | 29 | 11 |
Chemotherapy | No | No | Yes, neoadjuvant 3 courses doxorubicin/ifosfamide 75/10 and 1 course adjuvant | Yes, adjuvant 6 courses epirubicin/ifosfamide |