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Table 3 Summary of the parameter values and 95% confidence intervals for the LKB and RS models of the parotid glands for the endpoint of xerostomia and lacrimal glands for dry eye

From: NTCP modeling and dose–volume correlations for acute xerostomia and dry eye after whole brain radiation

Parameters

LKB model

D50 (Gy)

m

n

Xerostomia

23.4 (16.4–41.8)

0.89 (0.56–2.96)

1.0 (0.6–1.0)

Dry eye

61.2 (40.6–153.0)

0.77 (0.54–1.51)

1.0 (0.1–1.0)

Parameters

Relative seriality model

 

D50 (Gy)

γ

s

Xerostomia

24.9 (16.5–48.2)

0.26 (0.00–0.49)

10–4 (10–5 to 7 × 10–4)

Dry eye

63.9 (39.9–142.9)

0.34 (0.14–0.54)

10–4 (10–5 to 7 × 10–4)