Table 3 Results of the planning study for comparison (see text)
From: Radiotherapeutic treatment options for oligotopic malignant liver lesions
Technique | HDR-Brachytherapy (CTV ≡ PTV) | Cyberknife (CTV ≡ PTV) | VMAT (dHDR + 1 cm) | Tomotherapy (dHDR + 1 cm) |
|---|---|---|---|---|
Lesion ∅ 1 cm/2 cm (0.7 ml/5.2 ml) | 1 catheter | |||
Irradiation time [min] | 0.9/3.2 | 72/51 | 2.6/2.3 | 3.0/4.2 |
Dmean [Gy] | 56.3/58.1 | 28.6/34.2 | 23.9/22.8 | 25.5/28.2 |
Coverage 20 Gy [%] | 100/98 | 99.6/99 | 100/98 | 100/100 |
Liver mean dose [Gy] | 0.3/1.1 | 0.7/1.2 | 1.0/1.7 | 1.4/2.5 |
Volume > 10 Gy [ml (%)] | 0.5 (0.04)/6 (0.45) | 1.3 (0.1)/9.4 (0.7) | 17.5 (1.3)/54 (4) | 25 (1.9)/77 (5.8) |
Volume > 5 Gy [ml (%)] | 2 (0.2)/18 (1.3) | 8.4 (0.6)/62 (4.6) | 94 (7.0)/165 (12) | 100 (7.5)/236 (17.7) |
Volume > 2 Gy [ml (%)] | 24 (1.8)/161 (12) | 58 (4)/248 (19) | 187 (14)/282 (21) | 360 (27)/466 (35) |
Volume > 1 Gy [ml (%)] | 71 (5)/417 (31) | 220 (16)/444 (33) | 269 (20)/376 (28) | 413 (31)/560 (42) |
Kidney right Dmax [Gy] | 0.4/1.2 | 1.1/3.4 | 2.6/3.7 | 3.0/4.6 |
Stomach Dmax [Gy] | 0.1/0.2 | 0.8/1.4 | 0.5/1.4 | 1.3/2.1 |
∅ 3 cm lesion (16.5 ml) | 1/5 catheters | |||
Irradiation time [min] | 6.9/6.4 | 64 | 2.1 | 5.1 |
Dmean [Gy] | 58.2/50.1 | 31.7 | 21.5 | 32.5 |
Coverage 20 Gy [%] | 98/96 | 97.5 | 93 | 99 |
Liver mean dose [Gy] | 2.1/2.0 | 2.0 | 2.3 | 4.4 |
Volume > 10 Gy [ml (%)] | 24 (1.8)/22 (1.6) | 24 (1.8) | 81 (6.0) | 187 (14) |
Volume > 5 Gy [ml (%)] | 59 (4.4)/54 (4.0) | 138 (10.5) | 207 (15.4) | 373 (28) |
Volume > 2 Gy [ml (%)] | 443 (33)/416 (31) | 460 (35) | 403 (30) | 600 (45) |
Volume > 1 Gy [ml (%)] | 887 (66)/860 (64) | 657 (50) | 598 (40) | 733 (55) |
Kidney right Dmax [Gy] | 2.7/2.5 | 3.9 | 8.5 | 6.4 |
Stomach Dmax [Gy] | 0.5/0.5 | 2.2 | 0.9 | 3.1 |
∅ 5 cm lesion (75.9 ml) | 1/5 catheters | |||
Irradiation time [min] | 18.8/17.4 | 53 | 1.8 | 6.1 |
Dmean [Gy] | 58.7/46.3 | 34.2 | 22.1 | 31.3 |
Coverage 20 Gy [%] | 98/98 | 99.4 | 97 | 99 |
Liver mean dose [Gy] | 4.7/4.6 | 4.4 | 4.1 | 5.2 |
Volume > 10 Gy [ml (%)] | 128 (9.5)/120 (9.0) | 126 (10) | 159 (12) | 253 (19) |
Volume > 5 Gy [ml (%)] | 443 (33)/416 (31) | 446 (36) | 417 (31) | 653 (49) |
Volume > 2 Gy [ml (%)] | 1102 (82)/1048 (78) | 791 (63) | 712 (53) | 773 (58) |
Volume > 1 Gy [ml (%)] | 1304 (97)/1290 (96) | 937 (75) | 874 (65) | 959 (72) |
Kidney right Dmax [Gy] | 2.7/2.5 | 3.9 | 9.2 | 8.9 |
Stomach Dmax [Gy] | 0.5/0.5 | 2.8 | 2.9 | 2.7 |