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Table 1 Differences between proton beam radiotherapy and brachytherapy

From: X-change symposium: status and future of modern radiation oncology—from technology to biology

Proton beam therapy

Brachytherapy

External beam radiotherapy

Internal irradiation

Very small to large size PTVs

Very small to intermediate size PTVs

Commonly homogeneous dose distribution

Heterogeneous dose distribution

Almost all locations can be treated

Limited in locations to treat

Beam specific margins to account for dose distribution uncertainties

Limited or no PTV margins